Identical twins and Bayes ' theorem in the 21 st century [

نویسندگان

  • Michael McCarthy
  • Valentin Amrhein
  • Fränzi Korner-Nievergelt
چکیده

In a recent article in on "Bayes' Theorem in the 21st Century", Bradley Science Efron uses Bayes' theorem to calculate the probability that twins are identical given that the sonogram shows twin boys. He concludes that Bayesian calculations cannot be uncritically accepted when using uninformative priors. We argue that this conclusion is problematic because Efron's example on identical twins does not use data, hence it is not Bayesian statistics; his priors are not appropriate and are not uninformative; and using the available data point and an uninformative prior actually leads to a reasonable posterior distribution. Valentin Amrhein ( ) Corresponding author: [email protected] Amrhein V, Roth T and Korner-Nievergelt F. How to cite this article: Identical twins and Bayes' theorem in the 21st century [version 1; 2013, :278 (doi: ) referees: 1 not approved] F1000Research 2 10.12688/f1000research.2-278.v1 © 2013 Amrhein V . This is an open access article distributed under the terms of the , which Copyright: et al Creative Commons Attribution Licence permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Data associated with the article are available under the terms of the (CC0 1.0 Public domain dedication). Creative Commons Zero "No rights reserved" data waiver This work was funded by the Swiss Association Pro Petite Camargue Alsacienne and the Fondation de Bienfaisance Jeanne Grant information: Lovioz. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing interests: No competing interests were disclosed. 17 Dec 2013, :278 (doi: ) First published: 2 10.12688/f1000research.2-278.v1 1,2 1,2

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Two Techniques of Tonsillectomy Performed in Identical Twins: A Case Report

Introduction:Cold dissection (CD) and bipolar cautery dissection (BCD) techniques are two common surgical tonsillectomy procedures used in the clinic. Obstruction has become more prevalent as the major surgical indication and is most prominently observed in younger children.Case Report:  In this report, we aimed to explain the abovementioned surgical techniques in detail and compare the results...

متن کامل

Tay-Sachs Disease in Two Iranian Identical Male Twins; A Case Report

Background Tay-Sachs disease is an autosomal-recessive lysosomal storage metabolic disorder. The typical symptoms of the disease include ataxia, muscle weakness, and mental disorders. The severity of the clinical symptom relies on the enzymatic activity of residual Hexosaminidase-A. Case Presentation</...

متن کامل

مقایسه میزان بیان miR-106a، miR-24 و miR-107 بین دوقلوهای همسان در سنین مختلف

Background and Objective: Aging like many complex traits is the result of interaction between genome and environmental factors and epigenetic mechanisms as a central connector links these two markers. So far, investigations on age-related characteristics and biomarkers predicting survival and risk of death have been carried out, none of which led to an overall consensus among the researchers. I...

متن کامل

Nasal Septum and External Nasal Deformity Similarities in Monozygotic Twins and Paranasal Computed Tomography Analysis

Since identical twins occur as a result of the division of one egg, they have the same genetic structure. Therefore, their phenotypes and sex are also always the same. However, due to the effect of environmental factors, some of the characteristics of twins living in different regions appear to develop differently. In our case of 17-year-old maternal twins, we emphasized that nasal pathologies ...

متن کامل

Identifying the Zygosity Status of Twins Using Bayes Network and Estimation- Maximization Methodology

As the renaissance of family-based genomic research, identifying diseases and families for this kind of study becomes increasingly important. Recently, a large cohort of predicted twins, called the Marshfield Clinic Twin Cohort, has been generated by analyzing standard demographic information in an electronic medical record. However, one piece of critical information, the zygosity status (ident...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016